Recipient:

STTR Phase II Grant:

"Commercialization of Embryonic Kidney Cell Lines"

Abstract

 

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Welcome to Probetex:

Probetex, Inc. is a life science and contract research  organization providing reagents, biological samples, and histopathology services for the investigation of experimental models of disease.

Probetex's main focus is on renal diseases, however the company also specializes in liver, lung,  and cardiovascular diseases. Specialty areas of  include pre-clinical testing, animal models, histopathology, image analysis, cell culture, stem cells, assay development, and a variety of other disciplines.

Mission

Contact Probetex Inc.

MODULES

 

New Products!

Sheep Anti-Thy1 antibody to induce mesangial proliferative glomerulonephritis

Sheep Anti-GBM to induce immune-mediated glomerulonephritis

Sheep Anti-Fx1A antibody to induce experimental membranous nephritis

BioScout Products:

FITC-Sheep anti-Glomerular Basement Membrane (GBM)

FITC-Sheep anti-Extracellular Matrix (ECM)

Bioscout FITC-ECM + aminopeptidase (proximal tubules)

 


Company News:   

White Paper & News Releases

Recent Publications:

Velagapudi C, Nilsson R-P, Lee, MJ, Burns HS,  Arar M, Barnes VL, Abboud HE, Barnes JL. Reciprocal induction of simple organogenesis by mouse kidney progenitor cells in three-dimensional co-culture. Am J Pathol 180:819-830, 2012. (Cover Photo, February Issue).

McIntosh LM, Barnes JL, Barnes VL, McDonald JR. Selective CCR2-targeted macrophage depletion ameliorates experimental mesangioproliferative glomerulonephritis. Clin Exp Immunol 155:295-303, 2009.  Abstract     

Recent Publications Using Probetex Products and Services:

Nishikawa M, Yanagawa N, Kojima N, Yuri S, Hauser PV, Jo  OD, Yanagawa N. Stepwise renal lineage differentiation of mouse embryonic stem cells tracing in vivo development. Biochem Biophys Res Comm 417:897-902, 2012.

Lichtnekert J, Kulkarni OP, Mulay SR, Rupanagudi KV, Ryu M,    Allam R, Vielhauer V, Muruve D, Lindenmeyer MT, Cohen CD, Anders H-J. Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1. PLoS ONE 6(10): e26778. doi:10.1371/journal.pone.0026778. October 2011

Rufanova VA, Alexanian A, Ostendorf T, Bokenmeyer D, Prosser S, Miller B, Sorokin A: Endothelin signaling via guanine exchange factor C3G in renal glomerular mesangial cells. Can J Physiol Pharmacol 88:808-816, 2010.

Lindskog A, Ebefors K, Johansson ME, Stefansson B, Granqvist A, Arnadottir M, Berg A-L, Nystrom J, Haraldsson B. Melanocortin 1 receptor agonists reduce proteinuria. J Am Soc Nephrol 21: 1290-1298, 2010.

More.......

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      NEW! Kidney cell lines

      Glomerular mesangial

      Glomerular epithelial

      Glomerular endothelial

      Embryonic kidney stem cells

           metanephric mesenchymal

           ureteric bud

      Please inquire

Meetings & Events:

World Kidney Day

March 08, 2012

 

 

 

 

 

             

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